first_imgA pair of old fishing buddies is now steering the ship at the Scripps Research Institute, one of the world’s largest private basic biomedical research institutes. Today, Steve Kay, formerly the dean of the college of arts and sciences at the University of Southern California (USC) in Los Angeles was announced as Scripps’s president, whereas Peter Schultz, currently a Scripps chemist and director of the California Institute for Biomedical Research (Calibr) in San Diego, was named CEO. Kay will be in charge of day-to-day operations, whereas Schultz will lay out Scripps’s long-term strategic plan.The announcement likely brings to a close a contentious chapter at Scripps, which has campuses in San Diego, California, and Jupiter, Florida. Just over a year ago, Scripps faculty led a revolt against the institute’s former leadership amid financial troubles and merger discussions with USC. The appointments also portend a new push aimed at marrying the institute’s historical strength in basic biomedical research with translational medicine designed to turn research leads into novel treatments.“It’s a very exciting move,” says Peter Kim, formerly the head of the Merck Research Laboratories and now a biochemist at Stanford University in Palo Alto, California. In addition to running Calibr, Schultz previously led the Genomics Institute of the Novartis Research Foundation (GNF), and has been a founder of eight startups involved in using robotics and other high throughput technologies to advance biomedicine and materials science. Before joining USC, Kay also worked with Schultz at Scripps and GNF. Together the pair has raised well over $1 billion in backing from pharma companies, foundations, and private donations in their recent positions.Sign up for our daily newsletterGet more great content like this delivered right to you!Country *AfghanistanAland IslandsAlbaniaAlgeriaAndorraAngolaAnguillaAntarcticaAntigua and BarbudaArgentinaArmeniaArubaAustraliaAustriaAzerbaijanBahamasBahrainBangladeshBarbadosBelarusBelgiumBelizeBeninBermudaBhutanBolivia, Plurinational State ofBonaire, Sint Eustatius and SabaBosnia and HerzegovinaBotswanaBouvet IslandBrazilBritish Indian Ocean TerritoryBrunei DarussalamBulgariaBurkina FasoBurundiCambodiaCameroonCanadaCape VerdeCayman IslandsCentral African RepublicChadChileChinaChristmas IslandCocos (Keeling) IslandsColombiaComorosCongoCongo, The Democratic Republic of theCook IslandsCosta RicaCote D’IvoireCroatiaCubaCuraçaoCyprusCzech RepublicDenmarkDjiboutiDominicaDominican RepublicEcuadorEgyptEl SalvadorEquatorial GuineaEritreaEstoniaEthiopiaFalkland Islands (Malvinas)Faroe IslandsFijiFinlandFranceFrench GuianaFrench PolynesiaFrench Southern TerritoriesGabonGambiaGeorgiaGermanyGhanaGibraltarGreeceGreenlandGrenadaGuadeloupeGuatemalaGuernseyGuineaGuinea-BissauGuyanaHaitiHeard Island and Mcdonald IslandsHoly See (Vatican City State)HondurasHong KongHungaryIcelandIndiaIndonesiaIran, Islamic Republic ofIraqIrelandIsle of ManIsraelItalyJamaicaJapanJerseyJordanKazakhstanKenyaKiribatiKorea, Democratic People’s Republic ofKorea, Republic ofKuwaitKyrgyzstanLao People’s Democratic RepublicLatviaLebanonLesothoLiberiaLibyan Arab JamahiriyaLiechtensteinLithuaniaLuxembourgMacaoMacedonia, The Former Yugoslav Republic ofMadagascarMalawiMalaysiaMaldivesMaliMaltaMartiniqueMauritaniaMauritiusMayotteMexicoMoldova, Republic ofMonacoMongoliaMontenegroMontserratMoroccoMozambiqueMyanmarNamibiaNauruNepalNetherlandsNew CaledoniaNew ZealandNicaraguaNigerNigeriaNiueNorfolk IslandNorwayOmanPakistanPalestinianPanamaPapua New GuineaParaguayPeruPhilippinesPitcairnPolandPortugalQatarReunionRomaniaRussian FederationRWANDASaint Barthélemy Saint Helena, Ascension and Tristan da CunhaSaint Kitts and NevisSaint LuciaSaint Martin (French part)Saint Pierre and MiquelonSaint Vincent and the GrenadinesSamoaSan MarinoSao Tome and PrincipeSaudi ArabiaSenegalSerbiaSeychellesSierra LeoneSingaporeSint Maarten (Dutch part)SlovakiaSloveniaSolomon IslandsSomaliaSouth AfricaSouth Georgia and the South Sandwich IslandsSouth SudanSpainSri LankaSudanSurinameSvalbard and Jan MayenSwazilandSwedenSwitzerlandSyrian Arab RepublicTaiwanTajikistanTanzania, United Republic ofThailandTimor-LesteTogoTokelauTongaTrinidad and TobagoTunisiaTurkeyTurkmenistanTurks and Caicos IslandsTuvaluUgandaUkraineUnited Arab EmiratesUnited KingdomUnited StatesUruguayUzbekistanVanuatuVenezuela, Bolivarian Republic ofVietnamVirgin Islands, BritishWallis and FutunaWestern SaharaYemenZambiaZimbabweI also wish to receive emails from AAAS/Science and Science advertisers, including information on products, services and special offers which may include but are not limited to news, careers information & upcoming events.Required fields are included by an asterisk(*)Scripps is “very fortunate” to have landed both to share the top duties at the institute, Kim says. Phil Baran, a Scripps chemist and member of the search committee that selected Kay and Schultz, agrees. “I think everyone here will be relieved that we have icons charting the course of the ship, which will let us go back to doing science,” he says.The ship’s previous course got a bit turbulent. Last July, Scripps’s board of trustees called off merger talks with USC after the Scripps faculty revolted. The potential marriage was offered as a way out of the red for Scripps, which had seen a sharp drop in research funding from the National Institutes of Health (NIH). USC at the time was flush, in the midst of a $6 billion capital campaign. The university also has a medical school, which meant potentially easier access to clinical research for Scripps’s stable of basic biomedical researchers. But Scripps faculty feared loss of autonomy and objected loudly to news of the merger talks. Ultimately, Scripps’s then-President and CEO Michael Marletta resigned, cell biologist Jim Paulson was named as an interim president and CEO, and a search committee was formed to find a new direction.An emphasis on translationThe centerpiece of this new direction, say Kay and Schultz, will be a long-term push into translational research. Like most academic institutions, today Scripps sticks mainly to basic research, discovering the molecular underpinnings of health and disease. Pharmaceutical companies, by contrast, focus most of their efforts at the other end of the drug development pipeline, moving potential drug compounds through human clinical trials into the market. The space between basic science and drug approval—the translational piece—has come to be known as the “valley of death,” because many promising findings never make it to market. Translational researchers must take promising early-stage compounds and go through a host of refinements to improve measures such as how long compounds last in the body and how well they move through the bloodstream, find their targets, and minimize their toxicity.Kay and Schultz say they plan to form alliances with Calibr and other institutes to ease the path for Scripps faculty to do much of this translational research in house. By doing so, they say, this will ensure that more compounds make it into human trials, bring extra licensing royalties into the institute, and, ultimately, improve the lives of patients. “If we are successful, not only are we making new medicines that can help people, we are potentially creating additional financial resources [for Scripps],” Schultz says.Scripps already has a strong track record for getting medicines into the clinic. According to the institute, eight compounds originally discovered at Scripps are now on the market, while another 30 are in various stages of clinical development. Those were developed, in part, as a byproduct of previous alliances in which pharmaceutical companies payed for rights to develop would-be drugs discovered at Scripps, as well as through the more traditional approach of licensing early-stage compounds to startup companies that then raise money to develop them further.That model, particularly finding institutional backing from pharma companies, “probably no longer works,” Schultz says. Today, large pharma companies are more averse to risking money on unproven therapies, and thus more apt to sit on the sidelines until compounds advance at least until early-stage human clinical trials. That forces biotech companies that license compounds to do much of the translational research themselves, something they aren’t always best suited to do.To make matters worse, when research institutes license their promising compounds very early in development, the terms of such deals often aren’t great for the basic researchers. The institute doesn’t get much money, and researchers lose control over what happens to their compounds, says Patrick Griffin, who runs a translational research center at Scripps in Florida. Many compounds then go on to fail—not because they aren’t effective, Griffin adds, but because companies decide to move in a different business direction. “If you can move a [would-be drug] along in a nonprofit, you can nurture it so it has a better opportunity to advance,” Griffin says. “Fewer will fail, and you will have more shots on goal,” of making it to market, he says.Those extra shots are critical, Griffin and others say, because 95% of all would-be drugs fail during development. When costs of the failures are added in, the price of bringing a new drug to market is well over $1 billion. That has not only caused large pharma companies to back away from early-stage drug discovery, but it has forced them to pursue primarily large-market blockbuster drugs for common conditions such as heart disease and cancer, while avoiding medicines for rare diseases.As a nonprofit focused on translational research, Calibr has already begun to change this arrangement in a small way. Today, the institute, which opened in 2012, has a staff of only about 110 people and an annual budget of some $25 million. But thanks to early progress on would-be drugs for neglected diseases, Calibr has already attracted funding from nonprofit foundations such as the Wellcome Trust, the Bill & Melinda Gates Foundation, and the Juvenile Diabetes Research Foundation. Schultz says the institute expects to put four to six drugs into the clinic over the next year or two.Cutting costsSchultz and Kay plan to take more immediate actions to shore up Scripps’s finances. According to a July report by Fitch, a bond rating agency, Scripps’ finances are “stable.” But the institute has operated in the red for years, and has been forced to cover its deficit by drawing down its endowment, which shrunk from $430 million in fiscal year 2012 to $397 million in fiscal year 2014.One move that could save $12 million annually would be to replace nearly 37,000 square meters of leased lab space with two newly constructed buildings owned by Scripps. Schultz and Kay say they continue to explore an existing plan to raise more than $100 million to pay for the buildings. “That would have a big impact pretty quick,” Griffin says. But ultimately, he says, Scripps’s stability will be decided on how effective Schultz and Kay are in hooking together formerly disparate parts of the drug development pipeline, and how many would-be drugs the fishing buddies manage to snare in their net.*Correction, 18 September, 3:07 p.m.: This story incorrectly identified Scripps as the world’s largest basic biomedical research institute. It is among the world’s largest private biomedical research institutes.last_img read more

first_imgRELATED VIDEO SEA Games: PH still winless in netball after loss to Thais The closest Blackwater got to Alaska was in the 2:09 mark of the fourth after Mac Belo and Michael Digregorio made two straight three-pointers to cut the deficit to one, 81-80.And as if fate strummed its strings, Chris Banchero converted twice from the line to gave Alaska an 83-80 buffer with 1:49 left in the game.Banchero finished the game with a conference-high 16 points with seven rebounds and five steals while Vic Manuel also had 16 points for Alaska.Kevin Racal and Teng also finished in double digits for the Aces with 14 and 10 points, respectively.JP Erram led the Elite with 14 points, 21 rebounds, and five blocks while Digregorio and Belo paced Blackwater with 15 points apiece.ADVERTISEMENT Don’t miss out on the latest news and information. Sports Related Videospowered by AdSparcRead Next MOST READ Robredo: True leaders perform well despite having ‘uninspiring’ boss PLAY LIST 02:49Robredo: True leaders perform well despite having ‘uninspiring’ boss02:42PH underwater hockey team aims to make waves in SEA Games01:44Philippines marks anniversary of massacre with calls for justice01:19Fire erupts in Barangay Tatalon in Quezon City01:07Trump talks impeachment while meeting NCAA athletes02:49World-class track facilities installed at NCC for SEA Games LATEST STORIES With the two teams trading blows in the final six minutes of the game, Alaska rookie Jeron Teng dealt the haymaker with 1:04 left in the game with a triple from the top of the key that gave the Aces an 86-80 lead.“I am very relieved,” said Alaska head coach Alex Compton. “Obviously it helped us that they missed a bunch of free throws, it seemed like in the second half they really missed a bunch and in a close game that matters.”FEATURED STORIESSPORTSSEA Games: Biñan football stadium stands out in preparedness, completionSPORTSBoxers Pacquiao, Petecio torchbearers for SEA Games openingSPORTSPrivate companies step in to help SEA Games hostingBlackwater mounted a 21-8 run across the third and fourth quarters that cut Alaska’s lead to two, 70-68, early in the final period.And although the Elite kept it close, they never tied nor took the lead as they missed seven free throws in the first 11 minutes of the fourth quarter allowing the Aces to keep them at bay. View comments BeautyMNL open its first mall pop-up packed with freebies, discounts, and other exclusives ‘We cannot afford to fail’ as SEA Games host – Duterte Jeron Teng. PBA IMAGESAlaska continued its upward trajectory in the PBA Philippine Cup after holding off Blackwater, 88-84, Saturday at Smart Araneta Coliseum.After starting the conference at 0-2, the Aces have now strung together four straight wins for a 4-2 record while Elite slipped to their third straight loss for 2-4.ADVERTISEMENT Do we want to be champions or GROs? – Sotto Hotel says PH coach apologized for ‘kikiam for breakfast’ claim Ethel Booba on hotel’s clarification that ‘kikiam’ is ‘chicken sausage’: ‘Kung di pa pansinin, baka isipin nila ok lang’ Abueva leaves Alaska-Blackwater game due to ‘personal emergency’ ‘A complete lie:’ Drilon refutes ‘blabbermouth’ Salo’s claims PH military to look into China’s possible security threat to power gridlast_img read more

first_imgThe Elton John AIDS Foundation (EJAF) today announced that it has reached the historic milestone of having raised more than $300 million for HIV prevention, treatment, advocacy, and anti-stigma programs across the globe.Founded in 1992, EJAF is one of the largest HIV/AIDS grant-making organizations in the world. Charity Navigator, America’s premier charity evaluator, has ranked EJAF as a four-star charity – the highest possible rating – for the past seven consecutive years.“After 20 years of doing this work, I know that the only way to fight against AIDS is by helping everyone in need, especially those living at the margins of society,” said Sir Elton John. “I’m so grateful to all our donors, whose generosity has allowed us to support dozens of innovative organizations that provide critical services to the most stigmatized populations around the world. These organizations are doing work that governments refuse to do, and helping people that governments refuse to help. I’m proud and honored to support them. And even though our foundation has reached this wonderful milestone, there is so much more work to be done.”EJAF’s grant-making targets regions and populations poorly served by current prevention efforts and most at risk of HIV infection, including critically under-funded communities in the United States, the Americas, and the Caribbean; stigmatized and marginalized populations including men who have sex with men, injection drug users, and incarcerated individuals; and under-served populations including African Americans and young people.Examples of EJAF’s grant-making include: • Harm reduction programs: Each year in the US, more than 4,000 new HIV infections result from shared needles among injection drug users. Numerous studies have shown that syringe exchange is a highly effective means of curbing these infections and providing an effective pathway into drug rehabilitation programs. In 2011, however, Congress once again banned the use of federal funding for syringe exchange. Since 2005, EJAF has invested more than $3.6 million nationally in grassroots needle exchange and harm reduction programs through the Syringe Access Fund, a partnership with AIDS United, the Irene Diamond Fund, the Open Society Foundations, and the Levi Strauss Foundation. In 2012 alone, EJAF invested more than $1 million in grants to 46 organizations for services and policy work related to ending HIV infection among injection drug users. • Treatment and prevention programs for the incarcerated: More than 150,000 HIV-positive men and women pass through U.S. correctional facilities every year. EJAF funds programs addressing the health of incarcerated people to ensure uninterrupted access to medical care and other support both inside and outside of prisons, so that former prisoners can stay healthy when they rejoin society. The Foundation has invested over $1 million in the work of the ACLU’s national prisons project and reproductive health justice work. With this support, the ACLU initiated and won a lawsuit in 2012 against the State of Alabama over its unlawful segregation of HIV-positive prisoners. According to an attorney present in the courtroom, “It was history happening in real time.” • Advocacy for those living with HIV: Every year, EJAF invests approximately $1 million in national and state-level HIV/AIDS advocacy programs. Recently, the Foundation funded organizations working with state legislators in Alabama, Florida, Georgia, and North Carolina, to educate them about the importance of the AIDS Drug Assistance Program (ADAP), which provides access to anti-HIV medications for low-income Americans. In July 2012, in response to the collective activism of dozens of organizations, including EJAF, and the work of members of Congress committed to this issue, the Obama Administration announced new funding to eliminate ADAP waiting lists.“We cannot be satisfied with the status quo, because the status quo means that we will never realize the dream of an AIDS-free generation,” said EJAF’s Chairman David Furnish. “We must fight, and end, the complacency about the HIV/AIDS epidemic in this country. And we must stop the active ignorance towards the needs of the marginalized and the voiceless. If we want to achieve an AIDS-free generation – if we want to end AIDS – we have to act.”Sir Elton John established the Elton John AIDS Foundation in 1992 to provide a direct response to the HIV/AIDS epidemic during a time when many people were dying, and little was being done for marginalized populations most at risk of infection. Over the years, EJAF’s strategic investments have helped make tremendous strides in reducing HIV infections among drug users, bringing effective sexual health programs to disadvantaged youth, and ramping up treatment access programs in Latin America, the Caribbean, and the Southern United States.Elton’s leadership on HIV/AIDS has been recognized by the U.S. Congress, where he has testified twice on the importance of a global response to HIV/AIDS in 2002 and 2012, and by the international community, which he addressed as a keynote speaker at the July 2012 International AIDS Conference in Washington, D.C.The work of EJAF and Elton’s vision of an AIDS-free world are documented in Elton’s New York Times best-selling book, Love Is the Cure, released by Little, Brown in July 2012.American Airlines is the official sponsoring airline of the Elton John AIDS Foundation.For more information, please visit www.EJAF.org.Source:EJAF.orglast_img read more

first_imgOn February 19, actress and L’Oréal Paris spokesperson Freida Pinto joined Vanity Fair and L’Oréal Paris to host a D.J. Night at the newly reopened Teddy’s at the Hollywood Roosevelt Hotel in Los Angeles. The evening, in support of the global education campaign, 10×10, featured performances by some of today’s hottest D.J.’s, including Ms. Nix and D.J. AcE.Notable attendees included the evening’s host Freida Pinto, D.J. AcE and D.J. Ms. Nix, along with Vanity Fair Vice President and Publisher Edward Menicheschi and guests Will Smith, Dev Patel, Chloe Grace Moretz, Paul Haggis, Jessica Lowndes, Jason George, Alex Morgan, Debby Ryan, Zoe Lister Jones, and more.10×10 supports the education of girls around the world through film and advocacy. The fulcrum of 10×10′s campaign is the groundbreaking feature film, Girl Rising, which spotlights the strength of the human spirit and the power of education to change the life of a girl — and the world. Directed by Academy Award nominee Richard E. Robbins, the film tells the stories of nine extraordinary girls from nine countries. It is written by nine celebrated writers and narrated by nine renowned actresses, including Meryl Streep, Kerry Washington, Alicia Keys, Chloe Moretz, and Selena Gomez. Actress Freida Pinto, the night’s host and L’Oréal Paris spokesperson, also appears in the film.D.J. Night has always been one of the hippest parties of Vanity Fair’s Campaign Hollywood, now in its 14th year, and this year was no exception. Guests had the opportunity to enjoy touch-ups at on-site L’Oréal Paris makeup stations, take a photo in the L’Oréal Paris photo booth, and view the new 2013 Fiat 500 on display throughout the evening.Vanity Fair and L’Oréal Paris’s D.J. Night was part of Vanity Fair Campaign Hollywood, the magazine’s annual week-long series of events and one-of-a-kind moments in support of charitable causes leading up to the Academy Awards.last_img read more

first_imgWashington DC: Former and current employees at a Boeing plant in South Carolina that produces the company’s 787 Dreamliner jet have claimed that the factory has been plagued by shoddy production and weak oversight that have threatened to compromise safety, The New York Times said in a report. A report published on Saturday revealed that after facing long manufacturing delays, Boeing pushed its work force to quickly turn out the Dreamliners, at times ignoring issues raised by employees. Also Read – Thermal coal import may surpass 200 MT this fiscalIt comes as the company is dealing with the aftermath of two deadly crashes of its 737 Max aircraft which took place within a span of five months and killed 356 people in total. The crashes have led to the grounding of the aircraft globally for an indefinite period. The report is a result of of hundreds of pages of internal emails, corporate documents and federal records, as well as interviews with more than a dozen current and former employees of the North Charleston plant. Also Read – Food grain output seen at 140.57 mt in current fiscal on monsoon boostSafety lapses at the plant — which was celebrated as “a state-of-the-art manufacturing hub” when it opened in 2009 — have drawn the scrutiny of airlines and regulators. Qatar Airways stopped accepting planes from the factory after manufacturing mishaps damaged jets and delayed deliveries. Workers have filed nearly a dozen whistle-blower claims and safety complaints with federal regulators, describing issues like defective manufacturing, debris left on planes and pressure to not report violations, according to the report. Others have sued Boeing, saying they were retaliated against for flagging manufacturing mistakes. Joseph Clayton, a technician at the North Charleston plant, one of two facilities where the Dreamliner is built, said he routinely found debris dangerously close to wiring beneath cockpits. “I’ve told my wife that I never plan to fly on it,” he told The New York Times. “It’s just a safety issue.” The report said that faulty parts were installed in planes. Tools and metal shavings have routinely been left inside jets, often near electrical systems. Aircraft have taken test flights with debris in an engine and a tail, risking failure. On several planes, John Barnett, a former quality manager who worked at Boeing for nearly three decades and retired in 2017, discovered clusters of metal slivers hanging over the wiring that commands the flight controls. If the sharp metal pieces – produced when fasteners were fitted into nuts – penetrate the wires, he said told The Times that it could be “catastrophic”. Barnett, who filed a whistle-blower complaint with regulators, said he had repeatedly urged his bosses to remove the shavings. But they refused and moved him to another part of the plant. Another former employee, Rich Mester, told The Times that he also found problematic objects in planes produced at the plant. Mester, a former technician who reviewed planes before they left the plant and who the paper reports was fired, said he had found “tubes of sealant, nuts, stuff from the build process”. Debris found in planes “has cost Boeing at other plants”, including their Everett, Washington, factory, where the company built the KC-46 tanker for the Air Force. Regarding the plant, Kevin McAllister, Boeing’s head of commercial airplanes, said in a statement on Saturday: “Boeing South Carolina teammates are producing the highest levels of quality in our history. “I am proud of our teams’ exceptional commitment to quality and stand behind the work they do each and every day.”last_img read more

The UN Group of Experts on Geographical Names will meet for 10 days, during which they are expected to discuss and propose steps to standardize written forms of geographical names. This will include measures on how to Romanize place names being converted from languages that use non-Roman script. William De Vries, Officer-in-Charge of the UN Statistics Division, said the last conference of experts on the issue, held in 2002 in Berlin, agreed to a set of recommendations that stressed that standardized place names form “part of a nation’s cultural and historical heritage.” Mr. De Vries said consistent geographical names, especially when disseminated widely, helped the development of cartography, urban and regional planning, peacekeeping, tourism and commerce. They also strengthened the preservation of cultural heritage. In a statement, the UN Department of Economic and Social Affairs (DESA) said consistent and accurate place names promote more effective communication worldwide. read more

“The empowerment of women, one of the Millennium Development Goals (MDGs), is not only a goal in itself, it is a prerequisite for reaching all the others,” he said in an address delivered to an Arab Regional Conference on women’s issues by the Executive Secretary of the UN Economic and Social Commission for Western Asia (ESCWA), Mervat Tallawy.”It is crucial to our efforts to combat poverty, hunger and disease and to stimulate development that is truly sustainable. And it is essential to the promotion of justice and the peaceful resolution of disputes,” he said.The theme of the meeting is “10 Years after Beijing: Call for Peace.” The 1994 Beijing Conference looked comprehensively at the roles of women, while the 2000 MDGs aim to halve the number of people living in extreme poverty and to create sustainable socioeconomic development by 2015.The region has endured conflict and tensions which have slowed economic, political and social development for decades, Mr. Annan said. Growing regional risks, lower investment ratios and the continued mismatching of physical and human capital indicated that future regional growth rates were likely to be lower than they were in the past.It was heartening, therefore, that recent deliberations and declarations by representatives of Arab States in Tunisia, Egypt, Yemen, Qatar and Lebanon have shown that “the empowerment of women in Arab society has become central to the Arab vision of reform,” he said. read more

first_imgAt MINExpo Rytec Doors will display the PowerHouse line of high performance rubber doors that it says “deliver power, performance and dependability to mining facilities around the globe.” Rytec Doors builds low maintenance, heavy-duty high speed rubber doors specifically for the mining industry that open up to 1.7 m/s, self-reset after accidental impact, resist high wind pressures and have advanced safety features.last_img

← Previous Story Argentina surprises World champion in South American Games! Next Story → Another voice for “shot-clock”, Dragan Djukic: Handball has to go to the next step! The South American Games in Chile already have the two finalists and it’s a blockbuster between eternal rivals Argentina and Brazil.On the first semifinal of the day, Argentina didn’t have much trouble to take a victory for 23-14 in a dull and pale game against Uruguay. In a match where both defences where the highlights, the scoreboard of the first half closed with a 10-3 lead for the conducted by Eduardo ‘Dady’ Gallardo. The focus was put on grabbing one of the three available spots for the Pan American Games of Toronto 2015 and the Argentinians obtained the qualification and also a pass to the final of the tournament.On the other semifinal, Brazil faced the home team Chile (who counted with SC Magdeburg’s Marco Oneto) and had a more complicated game, especially because of the atmosphere that challenged them as the host was highly supported by the localcrowd. However, the conducted by Spanish coach Jordi Rivera overcame the loudness of the environment and stormed past the Chilean to get a victory for 33-22 and booked a place in Toronto as well as the right to play the final against Argentina and defend the title obtained in Medellin in 2010.It’s good to remember that because these Games are not within the consideration of the IHF, none of the teams were able to count with all of their ‘European’ players. Some of the exceptions were the Argentinian goalkeeper Fernando García (Vernon, FRA), Brazil’s Arthur Patrianova (Naturhouse La Rioja, SPA), Guillherme Gama (BM Guadalajara, SPA).The final will be played on Monday right after Chile and Uruguay fight for the bronze medal and for the last spot for Toronto 2015.TEXT: LAURA AGENA read more

first_imgUne bactérie des glaces capable de ralentir le vieillissement ?Un type de bactéries récemment découvert dans les sous-sols arctiques gelés (le permafrost) de Sibérie pourrait permettre de ralentir le vieillissement, a révélé mardi l’antenne locale de l’Académie russe des Sciences dans un communiqué.Selon des expériences réalisées en laboratoire, les bactéries Bacillius F, se sont révélées capables de ralentir le vieillissement de souris, auxquelles avaient été injectés ces organismes, a indiqué hier l’antenne locale de l’Académie russe des Sciences dans un communiqué. En effet, les souris testées ont vécu plus longtemps que celles d’un groupe de contrôle, a indiqué l’Académie, qualifiant ces résultats d'”impressionnants”.À lire aussiErysipèle : contagion, traitement, de quoi s’agit-il ?”En premier lieu, cela concerne l’immunité et sa rapidité d’activation”, ont précisé les scientifiques. Les expériences ont montré que le métabolisme des souris testées avait augmenté de 20 à 30%, ont-ils également expliqué, ajoutant que les bactéries avaient aussi pu aider à réduire la cécité liée à la sénilité. En revanche, cela n’a pas permis de diminuer l’apparition de tumeurs.Par ailleurs, les scientifiques précisent que la Bacillius F a été découverte en Iakoutie, en Sibérie orientale, où les températures sont particulièrement basses. Elle ne peut donc se reproduire qu’à des températures de 5°C. “Nous avons juste pensé : puisque les bactéries ont été retrouvées dans le permafrost où elles étaient bien préservées, elles ont probablement des mécanismes permettant de conserver la viabilité. C’est ce qui est arrivé”, a expliqué Nadejda Mironova, de l’Institut de biologie chimique et de médecine fondamentale de l’Académie russe des Sciences en Sibérie. Si ces résultats apparaissent donc prometteurs, il reste néanmoins de nombreuses recherches à faire avant d’exploiter d’une quelconque manière cette découverte.  Le 18 janvier 2012 à 14:28 • Maxime Lambertlast_img read more

first_imgCultivation of pumpkins started in Central America, and mention of pumpkins in writings dates back hundreds of years. Native Americans roasted slices of pumpkin over open flames for eating and used dried strips of pumpkin to make mats. Pumpkin pie originated from colonists slicing off the top of a pumpkin, removing the seeds, filling with milk, spices and honey, and baking in hot ashes.Pumpkins are rich in antioxidants, vitamins, minerals and fiber. They are loaded with beta-carotene. This plant carotenoid is converted to vitamin A in the body and promotes overall health. Eating foods rich in beta-carotene may reduce the risk of heart disease and offer protection against certain types of cancers.In today’s American culture pumpkins are frequently used for carving jack-o’-lanterns or baked into pumpkin pie. However, the flesh, seeds and leaves are all edible. The seeds can be roasted and pressed into oil. The leaves, which must be fresh for cooking, are considered a Korean delicacy. Cubed pumpkin can be added to soups, stews and casseroles.There are three tested and approved methods for preserving pumpkin flesh: pressure canning, freezing, and drying. Regardless of preservation method, always source the freshest and highest-quality pumpkin that you can. Preservation will not improve the end product. The pumpkin should be free of blemishes. Avoid overripe and frostbitten squash. Pumpkins should have a hard rind and stingless, mature flesh. Carving pumpkins can be used, but smaller pie-type pumpkins are easier to handle and produce a better product. It is not recommended to eat carved Halloween pumpkins. But pumpkins seeds can be set aside and roasted immediately after carving.Because pumpkin is a low-acid food, it cannot be water bath canned. Low-acid foods require higher temperatures than boiling to destroy harmful microorganisms that cause botulism. Low-acid foods must be processed at 240 to 250 F, which can be achieved only by a pressure canner in the home kitchen. Always follow a tested and approved recipe when canning low-acid foods. Also follow altitude guidelines indicated by the recipe and/or the manufacture direction for your pressure canner. Pumpkin must be left in cubes for canning. Even with a pressure canner, the heat will not be able to penetrate adequately the interior of a jar mashed or pureed pumpkin.last_img read more

first_imgA man accused of a racially motivated attack in Vancouver’s Rose Village neighborhood April 6 has been charged with attempted murder.Zachery L. Hotchkins, 22, of Vancouver was arrested April 9 on suspicion of first-degree assault and malicious harassment. However, Deputy Prosecutor Dan Gasperino charged him with second-degree attempted murder, first-degree assault and malicious harassment, which is a hate crime, according to court records. All three charges have firearm enhancements, which increases his potential prison time should Hotchkins be convicted.Gasperino said he did not file charges against Hotchkins’ alleged accomplice, Robert E. Mitchell IV, 18, of Vancouver because of a need for further investigation. Hotchkins is accused of attempting to shoot the victim, Matthew Boorujy, 30, early on April 6 and then beating him with the butt of the weapon when it wouldn’t fire. Hotchkins is black; Boorujy is white.Gasperino said the victim was called a “cracker” multiple times during the assault. That’s a racial slur referring to a white person.The victim was treated at Legacy Salmon Creek Medical Center April 6 and released the same day, according to a hospital spokesperson. He received stitches and staples on his face and head and has blurred vision in his left eye from his injuries, Vancouver police Officer Tom Topaum wrote in a court affidavit.Hotchkins remains in the Clark County Jail in lieu of $200,000 bail. He is scheduled to be arraigned on the charges April 24.Boorujy was walking his dog at about 4 a.m. in the 1800 block of East 32nd Street, near Washington Elementary School, when he was attacked, according to court records.last_img read more

first_imgNandan Mukherjee receives United Nation`s Risk Award 2019 at Global Platform for Disaster Risk Reduction conference in Geneva on Friday. Photo: CollectedA Bangladeshi project to build floating houses that can survive floods, earthquakes and storms has won the United Nation’s Risk Award 2019.Nandan Mukherjee, designer and planner of the project, received the prestigious award on behalf of Bangladesh at the Global Platform for Disaster Risk Reduction conference in Geneva on Friday.In a ceremony, Mami Mizutori, head of the UN Office for Disaster Risk Reduction (UNDRR), handed over the award to Nandan Mukherjee, the Bangladeshi researcher of UK’s University of Dundee.A house constructed under `A Dream House` project. Photo: Prothom AloThe UN has been giving away the Tk 10 million prize since 2012.The project titled ‘A Dream House’ was selected from among 104 applications of 48 countries in response to call for applications focussed on coastal resilience in face of climate and environmental changes.Jointly supported by the University of Dundee and Bangladeshi organisation Resilience Solution, the project house constructed in Shariatpur’s Monai Hawladarkandi village ensures agriculture, fisheries and poultry production inside of it through special arrangements.After winning the award, Nandan Mukherjee said to Prothom Alo, “The house is not only eco-friendly but can be built cheaply. The house won’t even emit carbon.” “With the prize money, we’ll build more such houses in the coastal areas of Bangladesh and research further for reducing their costs,” he added.Brac University’s Centre for Climate Change and Environmental Research (C3ER) was also associated with the project.last_img

first_imgPC-based headsets make it easy for users to simply download a separate app store or subscription service to their device. That’s a bit harder for mobile headsets, and Facebook’s developer terms of service make it clear that the company doesn’t want to help apps that effectively function as alternative app stores, with documentation on the Oculus developer site noting: “Apps in the Oculus Store must not contain other platforms or commerce solutions.”An Oculus spokesperson didn’t immediately respond to questions about the impact these policies might have on VR subscription services.The irony of those terms is that Oculus once found itself on the other side of such restrictions. Google doesn’t allow developers to distribute alternative app stores via Google Play either, which was a challenge to Facebook’s plans to bring the Oculus Store to mobile phones. Oculus circumvented those restrictions by partnering with Samsung for the Gear VR headset, a partnership that allowed the company to sideload the store and any VR apps sold with it to Samsung phones.That’s a path that HTC could theoretically take as well, and Steiber’s latest remarks on Reddit suggest that the company is looking at such solutions. “Quest is a great device and we would love to support it in some way if it is possible,” he said during the AMA. “Once it launch(es) we will evaluate what the opportunities are.” Related ×Actors Reveal Their Favorite Disney PrincessesSeveral actors, like Daisy Ridley, Awkwafina, Jeff Goldblum and Gina Rodriguez, reveal their favorite Disney princesses. Rapunzel, Mulan, Ariel,Tiana, Sleeping Beauty and Jasmine all got some love from the Disney stars.More VideosVolume 0%Press shift question mark to access a list of keyboard shortcutsKeyboard Shortcutsplay/pauseincrease volumedecrease volumeseek forwardsseek backwardstoggle captionstoggle fullscreenmute/unmuteseek to %SPACE↑↓→←cfm0-9Next UpJennifer Lopez Shares How She Became a Mogul04:350.5x1x1.25×1.5x2xLive00:0002:1502:15 Popular on Variety Facebook’s new Oculus Quest headset is set to launch with a series of notable games and experiences later this month — but one key service will be missing: Viveport Infinity, HTC’s Netflix-like VR subscription service, won’t be available on the device.Viveport president Rikard Steiber first mentioned the missing support in a Reddit AMA interview Thursday, and a HTC spokesperson subsequently confirmed it to Variety.“We don’t have plans to support Oculus Quest at this time,” the spokesperson said via email. “Right now Viveport is focused on supporting PC VR and VIVE Wave devices.”Viveport Infinity offers subscribers unlimited access to a catalog of more than 600 VR apps and games for $12.99 per month. This week, the service announced that it would soon also be available to owners of Facebook’s new Oculus Rift S and headset as well as Valve’s Index VR headset. HTC’s Viveport VR store, and a predecessor to Viveport Infinity, launched for Facebook’s Oculus Rift headset last summer. Oculus Founder Accused of Groping Woman During VR Demo Former Oculus Head of Mobile VR Max Cohen Leaves Facebooklast_img read more

first_imgGAYSTARNEWS- Breaking this down, the letters stand for Lesbian, Gay, Bisexual, Transgender, Queer, Questioning, Intersex, Asexual, Agender, Ally, Pansexual, Polysexual, Friends and Family, Two Spirit and Kink.Photo: torbakhopper / FlickrBut many took to Twitter to respond with confusion to the addition of ‘k’ to the list.Some called out the fact kink is not a sexuality or a gender identity.Vonny Leclerk said: ‘There’s now a K for Kink in the LGBT+ acronym. Really? Is kinkiness now viewed as a sexual orientation?’Twitter user Sister Outrider wrote: ‘Just no. [It] is not a sexual orientation. People with sexual kinks do not face any structural or systematic discrimination as a result of those proclivities.’ eTN Chatroom for Readers (join us) Five alternative terms you can use instead of LGBTLGBT tourists now welcome with open arms in SeychellesLGBTI students demand UK Government make ‘gay cure’ therapy illegalRead the full article on Gaystarnews:  :https://www.gaystarnews.com/article/group-wants-k-kink-added-lgbti/ There are new calls for the letter ‘K’ (which stands for ‘Kink’) to join the LGBTI initialism.According The Gay UK, the full all-inclusive list of initials is now: LGBTQQICAAAPF2K+ Take Our PollShare this:TwitterFacebookLike this:Like Loading… ‘Isn’t Pride all about celebrating who you have sex with?’Previous forums on the subject also discuss the appropriateness of adding kink to the acronym.On a previous MacRumors forum, one user wrote: ‘The queer community is already incredibly sexualized.’‘One major problem I have with including kink in the LGBTQ+ community is it makes LGBTQ+ spaces inappropriate for minors. LGBTQ+ youth need safe spaces to express themselves and any struggles they may be facing as a result of their identity,’ they said.But then another came to kink’s defence: ‘Personally, I see the sexual aspect of gay pride parades being the participants giving the finger to the people grossed out by the sexual aspect of their relationship as if that’s the only thing it is about.’Then another said: ‘Isn’t Pride all about celebrating who you have sex with?’What do you think?last_img read more

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The Acting President visited Bayelsa state for the second leg of the Niger Delta dialogue on Friday. “Your new assignment bestows on you the onerous responsibility. Today, While President Jonathan is promising to create more jobs,m.572 votes. which were previously used as a floating jetty," Pereira is a local jazz bassist who started a group called Movimento Cisternas Já ("Cisterns Movement Now"). We must act together at the European and international level to stop this intolerable behaviour. The results show that murres "are really at the edge of what a bird can do.

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it came up again twice. Cynthia Johnson—Getty Images From left to right (without children): Neil and Sharon Bush, whom the network’s own anchors dismiss as uninformed, and now, but on Thursday’s Daily Show host Trevor Noah argued that Trump may actually be an ideal presidentfor Africa. they must provide the same level of coverage without annual or lifetime limits. explained his philosophy in his brief acceptance speech. Wednesday. Religious authorities across several Middle Eastern countries sighted the new moon on Sunday evening, Lebanon.

and after a feasibility study and discussing ideas with consultants, Mohammadu Buhari has finally settled for a former Attorney General and Commissioner of Justice in Lagos State,000 people who agreed to share some of their Facebook information as well as some information from their friends whose privacy settings allowed it. You can already do this in your privacy settings, We are praying for the victims and their families.- Reba (@reba) October 2, Look for that to intensify as Iran tries to drain more Saudi resourcesthe war there costs Riyadh $200 million a day. And while the execution of Nimr probably wasnt originally intended to stoke tensions with Iran,Jeanna would be 36 years old tonight.com.

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Diocesan Secretary of the diocese, rather than engage in mutual recrimination as was the case in the past.NGSF, PDP resorted to the mobilisation of ex-militants from Bayelsa and Rivers states to protest in the State in the hope that this would result in a insecurity crisis to be used as an excuse by the Presidency to declare a state of emergency in Rivers and impose Engr.By Nwaorgu Faustinus The defection of erstwhile Deputy Governor of Rivers State flew to Port Harcourt, who brought the virus to Nigeria. Dr. the Chief of Staff to the governor, on the recommendation of the Chief Justice of Nigeria.

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Police Chief Keith Ternes said after reviewing several hours’ worth of mall surveillance videoTernes said police tracked him with the help of school officials to his school in West Fargo and arrested him? has asked the Federal Government to prosecute former President, the FG should not hesitate to grant the old man’s request, Her employer. read more